Visualizing Biological Copper Storage: The Importance of Thiolate-Coordinated Tetranuclear Clusters
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چکیده
منابع مشابه
Visualizing Biological Copper Storage: The Importance of Thiolate‐Coordinated Tetranuclear Clusters
Bacteria possess cytosolic proteins (Csp3s) capable of binding large quantities of copper and preventing toxicity. Crystal structures of a Csp3 plus increasing amounts of CuI provide atomic-level information about how a storage protein loads with metal ions. Many more sites are occupied than CuI equiv added, with binding by twelve central sites dominating. These can form [Cu4 (S-Cys)4 ] interme...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2017
ISSN: 1433-7851
DOI: 10.1002/anie.201703107